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BDNF upregulation The most well-documented mechanism of Semax is its ability to upregulate brain-derived neurotrophic factor (BDNF) a protein that plays a central role in neurogenesis, synaptic plasticity, and the formation and maintenance of neural connections

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Futhermore, cell labeling with Zombie Red, a fluorescent marker of cells with permeable extracellular membrane cell related to cell death induction, confirmed that glutathione did not altered cell integrity even at high concentrations