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[245] Weight-loss and diabetes drug litigation [edit] In August 2023, one of the first lawsuits was filed alleging that Novo Nordisk's Ozempic (semaglutide) and Eli Lilly's Mounjaro caused severe gastrointestinal side effects, including gastroparesis

This is because B12 is not a standard medication in the US or UK, so it is often made in small-scale compounding pharmacies rather than in large-scale manufacturing facilities

(2018) 9:e0212017

Dual incretin agonists achieve greater weight reduction than GLP-1RAs alone, and tirzepatide has now demonstrated cardiovascular safety noninferior to a proven GLP-1RA in patients with ASCVD as well as benefit in obesity-related HFpEF [40, 45]