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(116) observed that the administration of a combination of antibiotics (0.2 mg/mL gentamicin, 0.15 mg/mL ciprofloxacin, 2 mg/mL streptomycin, 1 mg/mL bacitracin) to specific pathogen-free (SPF) mice diminished serum IGF-1 levels and reduced bone formation

But it's unclear whether B vitamins have any added benefits for people with normal blood levels