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Standardized diagnostic, therapeutic, and monitoring protocols based on mitochondrial metabolic phenotypes should be established to enhance treatment outcomes and patient quality of life

In addition to those already noted for inborn errors of metabolism, several more are involved in folate metabolism (ALDH1L1 and ALDH1L2), lipid peroxidation (ALDH3B1), and retinol metabolism (ALDHA1)

28 d after BrdU injection, both BrdU+ and BrdU+/Prox1+ cell densities were significantly lower in DG-NR1KO mice than in controls (BrdU+: p = 3.6 10 4 , t (7.527) = 6.116P

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