not losing weight on compound semaglutide why am i Why am I doing everything right… and still not losing weight?” This is where semaglutide changes things. Because weight loss isn't just about discipline, it's Why Semaglutide Isn't Working: Plateau

Research Summary Retatrutide (LY3437943) is a triple incretin agonist targeting GLP-1, GIP, and glucagon receptors the first in its class

Once the medication is stopped, that effect evaporates within two to four weeks

Here are the most common ones: Headaches Usually appear early on and tend to fade with time Redness at the injection site Typically mild and goes away quickly Nausea Can happen if the dose is too high or taken on an empty stomach Water retention Some people notice slight puffiness in the first couple of weeks Tingling or numbness Often temporary and not a cause for concern Fatigue Especially if stacking with other peptides like CJC-1295 These side effects are usually manageable

Gastrointestinal Benefits: Semaglutide can alleviate gastrointestinal symptoms commonly experienced by individuals with diabetes, such as gastroparesis and constipation