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SmagaIPomiernyBKrzyzanowskaWPomierny-ChamioloLMiszkielJNiedzielskaEet alN-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: behavioral and biochemical analyses in rats

Annu Rev Pharmacol Toxicol 1998

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In another study of rats, following a 50 mg/kg dose of luteolin orally or intravenously, luteolin bioavailability was shown to be low, at 4.10%, with a rapid absorption and metabolism rate, large distribution, and high clearance, suggested to be owed to an enterohepatic recirculation [174]