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T2, immediately post-intervention

Results: Genetically predicted higher level of smoking initiation was significantly associated with reduced clozapine ( = 0.14, P = 4.53E-04) concentrations and norclozapine concentrations ( = 0.14, P = 3.33E-04), and increased coffee consumption was significantly associated with lower level of clozapine concentrations ( = 0.42, P = 1.70E-14), norclozapine concentrations ( = 0.27, P = 1.51E-07), and the metabolic ratio of clozapine to norclozapine ( = 0.15, P = 5.35E-07), survived after the Bonferroni correction ( P = 0.05/6 = 0.008)

Studies show that around one in four adults with asthma continues to smoke, despite their respiratory diagnosis

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements