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Oxidative phosphorylation A metabolic pathway that produces ATP from the oxidation of acetyl-CoA and the transfer of electrons to the electron transport chain via NADH and FADH 2

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AMPK activation (AICAR): a well-characterised AMP-activated protein kinase agonist used extensively in cellular energy-sensing research

Females of childbearing potential must use two reliable forms of contraception simultaneously during oral tretinoin therapy and for one month following discontinuation of therapy, unless abstinence is the chosen method