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Indeed translocation of mTORC1 from the cytoplasm to the lysosome, a rich compartment in amino acids, is critical for mTORC1 activation ( per se is also able to regulate mTORC1 activity ( In brief, activation of the GCN2-ATF4 amino acid stress pathway and inhibition of protein synthesis through inhibition of mTORC1 demonstrates the strong proteogenic role played by cysteine in tumor cells

[DOI] [PubMed] [Google Scholar] 40.Findlay R.J., Macrae E.H.R., Whyte I.Y., Easton C., Forrest L.J

This symptom may relate to the medication's effects on gastric emptying, changes in blood pressure, or glucose fluctuations