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Given the expression of the GHSR-1a in less accessible brain areas, particularly in relation to incentive salience, there is an impetus to investigate BBB penetrability of ghrelin ligands further

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GHRP-6 activates the full program Gastric motility: Accelerated gastric emptying via vagal ghrelin receptors directly applicable in dysmotility research Historical/reference work: Decades of foundational GH secretagogue literature used GHRP-6 as the reference compound