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This heavy metal-induced mitochondrial damage creates a devastating synergy with viral infections

Ethics declarations Ethics approval and consent to participate All procedures performed in studies involving human participants were in accordance with the ethical standards of Royan Institute and the 1964 Helsinki declaration and its later amendments or comparable ethical standards (Ethics approval number: IR.ACECR.ROYAN.REC.1397.156)

29,179 In chronic high-oxygen exposure or paraquat-induced injury, 180,181 SIRT1 activation can worsen mitochondrial impairment and ROS generation by modulating apoptosis-related proteins and inhibiting Nrf2-mediated antioxidant expression

L-carnitine L-tartrate (LCLT) appears particularly effective for resistance training, while propionyl-L-carnitine might better support endurance activities