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BMJ 324:15125, PMID: 12077044 Passeri M, Cucinotta D, Abate G, Senin U, Ventura A, Stramba BM, Diana R, La Greca P, Le Grazie C (1993) Oral 5-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study
Second, safety and ethical concerns persist, particularly for injectable systems such as PEGylated uricase, where immunogenicity and long-term tissue accumulation necessitate rigorous riskbenefit analyses
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Moisture-sensitive residues Certain amino acids are hygroscopic, meaning they readily absorb moisture from the surrounding air
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