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Severe gastrointestinal symptoms causing inability to maintain adequate fluid intake require assessment, as there is a risk of acute kidney injury with significant dehydration

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The number of confirmed hypoglycemic events per patient-year was 1.8 for IDegLira, 0.2 for liraglutide, and 2.6 for insulin degludec, confirming the assumption that a combination of insulin and a GLP-1 receptor agonist would have a higher risk of hypoglycemia