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Dermoscopy in Irritant Reactions In clinical terms, irritant reactions are characterized by the burnt appearance of the skin, with cigarette paper texture, typically without erythema (or scant erythema) and greater or lesser associated follicular reaction.1 The dermoscopic characteristics of irritant reactions are less defined than those of allergic reactions, probably because they are associated with a wide range of epidermal changes.5,6 In an attempt to define them, Corazza et al.6 performed patch tests with sodium lauryl sulfate 2.5% applied over 48hours as a positive control for irritant tests but found no clinical differences with irritant reactions in daily clinical practice