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To address this issue, we performed a sensitivity analysis using Firths penalized likelihood logistic regression, which corrects for sparse data bias

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The tobacco industry stonewalled, hankering back to the days when you listed health benefits on a pack of cigarettes. While the US was still debating the health effects of tobacco and smoking, in 1957, the then surgeon general Leroy Burney declared it the official position of the US Public Health Service that evidence pointed to a causal relationship between smoking and lung cancer. After growing pressure from medical groups, the then President John F