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NRT nasal sprays similarly produce rapid high levels and may best be used after feeds

According to Professor Bernd Mayer of the Department of Pharmacology and Toxicology at Karl-Franzens University Graz (Austria), Smoking a cigarette results in uptake of approximately 2 mg of nicotine and gives rise to mean arterial plasma concentrations of about 0.03 mg/L (30 ng/mL). Mayer is a known expert on nicotine, but other researchers have slightly different answers

Over time, this can lead to a higher risk of heart disease

The more accurate framing is that it's a public-health policy question European harm-reduction models have already worked through, methodically, without a single podcast episode