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The smoking initiation-associated SNV, rs12780116, was an eQTL for BORCS7 in four brain tissues, and NT5C2 in the cerebellar hemisphere (A allele P = 4.5 10 7

It is the first time the Food and Drug Administration has sought input on a modified risk tobacco product application, a move thats being watched by the public health community and tobacco companies, which are looking for new products as they face declining cigarette demand due to tax hikes, health concerns, bans, and social stigma