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Sure, 5 grams of sugar a couple times a month probably wont have a long-term impact, but if youre consuming this daily while intermittent fasting, or it starts to trigger a sugar craving, then having this gum could be causing more harm than good

the cause remains unclear and may relate to gastrointestinal effects, dehydration, or other factors

Finally, the results of one randomized controlled trial in 601 patients with common forms of retinitis pigmentosa indicated that supplementation with 400 IU/day of synthetic vitamin E (equivalent to 180 mg/day of RRR --tocopherol) modestly but significantly accelerated the loss of retinal function compared to placebo (123)