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The method for synthesizing Cagrilintide according to claim 1, wherein the coupling reaction specifically comprises: weighing 5.71g of Rink AmideAM resin (the resin substitution degree is 0.35mmol/g) and adding into a solid phase reactor, and adding 50mL of DCM to swell the resin for 0.5 h

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Some pharmacies use methylcobalamin instead of cyanocobalamin, which is a different form of B12 with slightly different pharmacokinetics