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62, 63 The early production of CCL2 after an acute cigarette smoke exposure in mice correlated with the influx of monocytes/macrophages (and, based on the morphological criteria, presumably also DCs) in lung tissue and lumen, similar to what has been observed in allergic lungs

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Professor Sanjay Agrawal from the Royal College of Physicians concluded: Every cigarette smoked costs precious minutes of life, and the cumulative impact is devastating, not only for individuals but also for our healthcare system and economy