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The overall annual average decline in ASDR burden is 0.72%, particularly reaching the fastest decline rate (-1.11%) from 2011 to 2014, after which it entered a relatively moderate period (-0.68%) (Supplementary file Figure SF7)

We defined acceptance rate as the proportion of participants who accepted one of the three offered products and signed the respective intervention consent

This creates a perfect storm for liver damage, even at doses that would normally be safe

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