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JAMA, 321(15), 1466-1480
Exendin-4, GLP-1 (7-36), and GLP-1 (9-36) increased DNA synthesis in hCAECs with subsequent cell proliferation;(Erdogdu et al., 2010) while exendin-4 and GLP-1 (7-36) protected hCAECs against lipoapoptosis (Erdogdu et al., 2013)
23 While the clinical and safety impact of antiliraglutide antibodies is unknown at this time, further study of this phenomenon is warranted
Of particular interest, the discovery of GLP-1 receptor expression in the myocardium and in the vascular endothelium suggested possible roles of GLP-1 in the cardiovascular system and multiple preclinical studies support cardioprotective effects of native GLP-1 (Fig
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