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showed a compliance rate of 7.1 months for monthly heartworm preventatives in Australia, while a similar study by Mwacalimba et al

Severe vitamin B12 deficiency can lead to memory loss, joint pain, and vision problems, among other complications

This argument is plausible it reflects a well-documented problem in drug development where unpatentable compounds struggle to attract industry funding regardless of their scientific merit but it should be noted that this explanation, while widely discussed, has not been formally established in the published literature as the primary reason for the evidence gap

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