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When the effect of cigarette number/per day on cardiorenal risk was evaluated, CV and mortality risk increased by 4% for each cigarette per day consumed in current smokers, whereas CV events risk only was increased by 1% for one more cigarette, in former smokers

155 Epigenetic control of inflammation in the lung has been observed by post-translational histone acetylation, allowing unwinding of the chromatin structure and an enhanced transcription of pro-inflammatory genes