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Similar patterns of cellular damage are observed in both metabolic disorders and PD, including mitochondrial dysfunction, impaired autophagy, oxidative stress, endoplasmic reticulum stress, and gut microbiota alterations

The results showed that the CREKA and GALA modified with redox-responsive complex had excellent transfection efficiency and protected siRNA from the degradation of RNA enzymes (Zhang et al., 2021)

In 2021, an estimated 15.1 million children and young adolescents (aged 5-14 years) and 21.4 million older adolescents (aged 15-24 years) had overweight or obesity in the USA [1]

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