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For instance, one such non-peptide-based GLP-1RA formulation, called Orforglipron (LY3502970), has been developed and is currently undergoing Phase III clinical trials (Wharton et al., 2025

deleting or inhibiting YTHDF1 in dendritic cells preserves cross-priming capacity and augments CD8 + infiltration after radiotherapy or radio-immunotherapy, with patient correlative data reinforcing in the same direction