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NIH ODS Fact Sheet for Health Professionals: Vitamin B12 (updated 2024)

Dosing and How to Take Them Semaglutide Dosing For weight loss (Wegovy): Start: 0.25 mg weekly for 4 weeks Increase gradually to 2.4 mg weekly Take as injection under the skin once per week Also available as daily pill (Rybelsus) for diabetes Tirzepatide Dosing For weight loss (Zepbound): Start: 2.5 mg weekly for 4 weeks Can increase up to 15 mg weekly Take as injection under the skin once per week Only available as injection, not as pills Both medications work best when you increase the dose slowly

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