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This research is preliminary

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These disturbances, compounded by impaired mitochondrial fatty acid oxidation, ultimately contribute to dyslipidemiacharacterized by elevated serum triglycerides, LDL cholesterol (LDL-C), and total cholesterolwhich accelerates pathological processes such as atherosclerosis and fatty liver disease [119, 120]

In macrophage-specific PPAR knock-out mice, granuloma formation was much more extensive than in the wild-type after MWCNT challenge (Soliman et al., 2020)