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The researchers argued, The increased risk associated with short-acting analogs needs further studies to validate these findings. The possible protective effect of GLP-1 receptor agonists against AMD may be primarily attributed to their ability to mitigate chronic retinal inflammation and oxidative stress, which are pivotal in the pathogenesis of AMD, the authors explained in their paper

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This 56-week study included 1,225 participants with type 2 diabetes who were already taking metformin (with or without thiazolidinediones)