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Independent work has reported acceleration of tendon-to-bone healing in rotator cuff models in rats [Chang et al., Journal of Applied Physiology, 2011]

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Increased abundance of Gram-negative microorganisms leads to increased release of lipopolysaccharide (LPS), which disrupts the integrity of the intestinal mucosal barrier and triggers neuroinflammation and neuronal death through a series of steps (54)

Los estudios in vitro y en modelos animales han revelado que su mecanismo de accin no depende de un solo receptor, sino de una cascada de sealizacin intracelular compleja