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days 1 to 30): 3 mg orally once a day Dose escalation (days 31 to 60): 7 mg orally once a day Maintenance dose (day 61 and onward): If no additional glycemic control is needed: 7 mg orally once a day If additional glycemic control is needed: 14 mg orally once a day SUBCUTANEOUS: Ozempic Injection: Initial dose: 0.25 mg subcutaneously once a week for 4 weeks, then 0.5 mg subcutaneously once a week Maintenance dose: 0.5 to 2 mg subcutaneously once a week, based on glycemic control If additional glycemic control is needed after at least 4 weeks on the 0.5 mg dose: Increase to 1 mg subcutaneously once a week

GLP-1s: an attractive high-growth industry for all investors Overall, there remains considerable opportunities for investment across the GLP-1 value chain, despite this market becoming increasingly crowded

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L.Van OudenhoveL.TackJ.et al (2018)