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Introduction Direct involvement of chemicals in the tobacco smoke with cancer has been shown since the 1970s and considered as pleiotropic carcinogens that cause DNA damage ( In this study, we will highlight genomic and molecular features, which can be used to develop approaches to predict cancer after long-term tobacco smoke exposure

Finally, not staying hydrated can also play a role

Smokers and ex-smokers with CB had an increased risk of death (HR 2.89 and 1.69, respectively) compared with never-smokers without CB