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What to expect next Industry observers and regulators expect the next 12 months could significantly reshape the market as generics and authorised lowercost products reach pharmacies and as SAHPRA continues to review applications

In the landmark 68-week STEP1 obesity trial, participants on 2.4mg recorded a mean body-weight reduction of 14.9%, versus 2.4% on placebo[1]. 50% lost 15% or more of their body weight, and 69% lost at least 10%[1]

When to choose each option Researchers who follow non-standard protocols, those doing customized semaglutide regimens or working with unusual concentrations, often find that home prefilling is the only practical option since pharmacies prepare fixed-dose syringes

1 It should not be used in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia, type 2