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A meta-analysis published in PMC concluded that weight regain is common and drug-dependent following discontinuation of anti-obesity pharmacotherapies, emphasising the need for sustained, long-term treatment strategies to manage obesity as a chronic disease

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When exogenous testosterone enters the bloodstream, the brain detects it and reduces production of the very hormones needed for sperm production

Diuretics, often used to treat high blood pressure and heart failure, promote water loss through increased urination