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First, many e-cigarettes have poor nicotine delivery profiles, and our results suggest that those products may be less effective in helping smokers change their behavior and associated toxicant exposure, Cobb said

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The assumption is that since nicotine is the addictive component in cigarettes, introducing a product that has 25 times less nicotine than a traditional cigarette would lead to less nicotine dependence

For example, some e-cigarette flavorings may be safe to eat but not to inhale because the gut can process more substances than the lungs