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Together, these findings support the hypothesis that decreased endogenous GLP-1 signaling promotes/facilitates drug seeking and that activating central GLP-1-producing neural circuits may attenuate cocaine-seeking behavior during abstinence

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The practical questions are: what receptor pathway does it use, what human data exists, what is the current approval status, and how does it compare with approved GLP-1 options

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Two of the most important ones are GLP-1 (Glucagon-Like-Peptide-1) and GIP (Glucose-dependent Insulinotropic Polypeptide)

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