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Neurorestoratives act on the machinery and the accumulated state of the tissue, including the energy supply of neurons, the burden of damaged proteins, the level of inflammation, and the health of small blood vessels

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Whether its a bone that fails to heal swiftly or a fracture that realigns incorrectly, approximately 5-10 % of all fractures are associated with impaired healing [2]

Interestingly, in breast cancer, the combination of IL-15 and radiation has been recently demonstrated to enhance response to radiation, improve survival and enhance CD8+ T cell infiltration (77), suggesting that this metformin-mediated increase in IL-15 secretion may in part mediate the radiosensitising effect of metformin