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A systematic review of 32 studies on the relation between smoking and hair health involving a total of 23,685 patients revealed that smoking is associated with a higher prevalence of alopecia and premature hair graying (PHG)

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Although all studies consistently indicated a statistically significant positive association between current e-cigarette users with a smoking history and the prevalence of COPD, the included studies showed high heterogeneity ( I 2 = 95.82%), and the prediction interval for the ORs was 0.86 to 5.47 (Figure 3C)