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According to the World Health Organization, smoking including inhaling smoke second-hand kills more than 8 million people each year

[PMC free article: PMC2916847] [PubMed: 20700436] [CrossRef] Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PAF, Breslau N, Johnson EO, Hatsukami D, Pomerleau O, et al

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While the liver mostly processes buprenorphine, some of it is excreted through the kidneys