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The methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) identified 2 copies of chromosome 15q11, and an abnormal DNA methylation with 2 methylated copies
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In glaucoma, alterations in the balance between MMP and TIMP as well as the reduced MMP activity in the aqueous humor have been observed, contributing to abnormal ECM buildup, increased aqueous humor outflow resistance, and elevated IOP [76]
GLP-1 enhances glucose-dependent insulin secretion from pancreatic beta cells, inhibits glucagon release from alpha cells, and slows gastric emptying, thereby aiding in blood glucose regulation
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