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Over time, these changes may increase the risk of cavities

PE-22-28 (Mini-Spadin) blocks TREK-1 potassium channels with ~100-fold greater potency than its parent compound, demonstrating BDNF upregulation, rapid neurogenesis within 4 days, and cognitive benefits in stroke models (Djillani et al., 2017 in Frontiers in Pharmacology)

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He shares PET imaging data, results from a 6-month MCT trial in mild cognitive impairment, and why ketogenic and ketone-based therapies could help preserve cognition in neurodegenerative diseases, especially when combined with exercise and modest carbohydrate restriction