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Researchers reviewing safety information should consider the full adverse event profile, including cardiovascular observations, discontinuation rates, laboratory measures and any serious adverse events reported in trial data

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The acyl-CoA synthetase long-chain family member 3 (ACSL3), which is critical in converting fatty acids into fatty acyl-CoA esters, enables cancer cells in the lymph to incorporate oleic acid in the cell membrane to protect them from ferroptosis (62)