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Notably, increases in opioid overdose emergency admissions and deaths following lockdown have been reported in some US states [64,65,66], while German data from the first 6 months of 2020 indicate a 13% increase of drug overdose deaths as compared to 2019 [67], which may be due in part to changing purity and resulting uncertainties for titration [18]

Marijuana use can affect how a patient responds to anesthesia, often requiring higher doses for effective sedation

This can provide insight into the link between retail exposure, craving, and smoking, and yield information about targets for intervention

They can be disabling in some cases