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Kligerman said radiologists still have an important role to play in looking for lung injury patterns consistent with possible EVALI and asking doctors to ask about vaping when they are talking with patients

TEREA Traditional tobacco feel Some long-term HEETS users prefer the slightly drier, sharper character produced by older blade-based IQOS devices, especially with stronger tobacco blends

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Key to this approach are (i) the use of agreed reference products for comparison, ideally authorized MRTPs, and (ii) bridging methodologies that allow to compare a cMRTP with the reference products based on a limited number of studies (see challenge 4)