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Table of Contents Understanding Weight Loss Plateaus on Ozempic Ozempic (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed in the UK for the treatment of type 2 diabetes mellitus

The simple answer after the extensive research is Yes , semaglutide is FDA-approved for weight management in individuals without diabetes

It is a chemical inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which catalyzes the methylation of nicotinamide using S-adenosylmethionine as the methyl donor

And weeks 36 through 48 approached a plateau in most participants, with weight either stabilizing or declining very slowly