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Dr Markku Lhteenvuo, a research director at the University of Eastern Finland, said: It is possible that, in addition to factors such as reduced alcohol consumption, weight loss-related improvements in body image, or relief associated with better glycaemic control in diabetes, there may also be direct neurobiological mechanisms involved, for example, through changes in the functioning of the brains reward system. Responding to the findings, experts urged caution, including Prof David Nutt, who is the head of the neuropsychopharmacology unit at Imperial College London and chair of the independent scientific committee Drug Science

Bremelanotide is FDA-approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women, and the same molecule has been used more broadly under clinical supervision

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These drugs may be heralded as gamechangers when it comes to getting people to lose weight, but several trials have shown clear weight regain when treatment is withdrawn