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Veterans taking Ozempic might encounter side effects including gastroparesis (stomach paralysis), ileus, intestinal blockages, gallstones, biliary issues, and bowel obstructions due to the drugs mechanism of slowing digestion

Another effect of decreased GI motility is reflux, or GERD

Blood Sugar Swings In people with diabetesor those prone to reactive hypoglycemiaGLP-1 medications can cause: Rapid glucose shifts Subtle hypoglycemia Low or rapidly falling blood sugar often presents as: Irritability Anxiety Short temper Feeling on edge Patients may not recognize this as a blood sugar issue, especially if they are not using continuous glucose monitoring

Aetna's clinical policy bulletin (CPB 0784) now expects documented weight management attempts of at least 6 months before approving GLP-1 coverage on most plans (up from 3 months on some 2025 plans)