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doi: 10.1007/BF02252926

Can invalid bioactives undermine natural product-based drug discovery

CLU encodes clusterin, a molecular chaperone involved in A clearance and in cholesterol metabolism and trafficking, and TREM2 , which encodes a receptor primarily expressed in microglia that can be activated by damage-associated lipids and trigger the removal of A plaques (Wang et al., 2015)

Memory formation and recall Preclinical studies have shown Dihexa may significantly improve both short- and long-term memory in animal models with chemically induced amnesia