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Lung surgery, painful chemo, radiation, watching her lose her long beautiful hair, Melinda went through hell and she was so brave

A multinational RCT of more than 8,000 smokers found no significant increase in rates of moderate-to-severe neuropsychiatric adverse events with either varenicline or bupropion relative to nicotine patch or placebo in those with or without psychiatric disorders (although the trial excluded patients with symptomatically unstable psychiatric conditions) [57]