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In order to investigate the effects of smoking on sperm parameters, we searched the literature for studies that compared differences between smokers and non-smokers, since simply comparing data from smokers with WHO reference values cannot provide a true reflection of the changes caused by smoking

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Diketones are not present in all e-liquid, but a 2014 study by cardiologist Konstantinos Farsalinos concluded that diacetyl and acetyl propionyl are avoidable risks. Following that, many manufacturers reformulated their products and eliminated the diketones

[73] [74] The smoking age in South Carolina was 18 in 1988